Home Health & Disease DNA Type 2 Diabetes Test

DNA Type 2 Diabetes Test


Does diabetes run in your family? Take this DNA test to understand your genetic risk for type 2 diabetes.

• Includes variants that influence glucose levels, fat metabolism, insulin production and response to insulin
• 70% chance of developing type 2 diabetes when both parents have the disease
• Private and confidential online results
• Painless sample collection



Detailed Description

Type 2 diabetes is a metabolic disorder that disrupts the body’s normal glucose and insulin balance. It is generally associated with unhealthy lifestyles and extra body weight, but genetic variations can also increase your risk, regardless of your lifestyle.

Glucose is the primary source of energy used by the cells in our bodies. The levels of this simple sugar are regulated by the hormone insulin, produced by the beta cells of the pancreas. People with type 2 diabetes do not make sufficient amounts of insulin, therefore have consistently high blood sugar levels.

With a simple mouth swab you can find out whether you have inherited DNA changes that increase your risk of type 2 diabetes.

The Genetics 

Genetic variations can affect our glucose and insulin levels, sensitivity to dietary fatty acids, and the way our body responds to insulin, resulting in increased risk of type 2 diabetes. Knowledge of genetic variants that increase your risk of type 2 diabetes allows you to make lifestyle changes today, to reduce your risk of this debilitating condition.
Variants Tested:
Gene(s) Tested Effect
ACC2 Reduced response to insulin
ADCY5 Inhibited secretion of insulin
FABP2, FTO Increased uptake of saturated fats
ADIPOQ, CRY2, FADS1, G6PC2, GLUT2, MTNR1B, PROX1, TCF7L2 Increased fasting glucose levels
GCKR Reduced fasting glucose levels
GCK, HNF4A Reduced pancreatic beta cell function
GLIS3, IRS1, SLC30A8 Disrupted insulin production/signalling/storage
SHBG Increased sex hormone binding globulin
MADD Impaired proinsulin-to-insulin conversion
SOD2 Increased reactive oxygen species
HIF1A Resistance to hypoxia


Discover More

How many diabetes risk factors do you have?

  • Genetic variation
  • Family history of type 2 diabetes
  • Obesity and fat accumulation (around the abdomen)
  • Lack of physical exercise
  • Ethnicity (Africans and American Indians have a higher risk)
  • Prediabetes – elevated blood sugar
  • Gestational diabetes
  • Polycystic ovarian syndrome

How it Works

STEP 1.ORDER YOUR KIT: Purchase your kit online.


Quick and painless DNA sample collection in the comfort of your own home. Mail your sample back to our lab for testing.


Receive your results by mail or email, or view online.