Genetrace Celiac Disease Test Overview
Why get tested for gluten sensitivity?
Whether you eat at home or eat out, wheat-based products can make up a large part of our diet. Popular foods including breads, pastries, and pasta are all made with wheat and contain gluten, proteins found in grains especially wheat.
With the recent rise of the gluten-free fad, it’s easy to be caught up in the gluten-free craze. But, is gluten really bad for you? The answer to this question depends on your genetics. People who have celiac disease have severe reaction to gluten, ranging from digestive symptoms like stomach cramps and bloating to more serious issues like inflammation in the lining of the intestine. That’s because in people with celiac disease make abnormal proteins that recognize gluten as being foreign and mounts an immune response. This is known as autoimmunity.
That’s where the bad rap for gluten stops. Gluten is bad if someone has celiac disease. But, if you don’t have celiac disease or gluten sensitivity, gluten is a healthy plant based protein with several health benefits.
Do you want to know if you should avoid gluten?
Gluten-free diets are really a fad, because they are only necessary for people who are sensitive to gluten. Yet, companies that make expensive gluten-free products often promote them irresponsibly, tricking many consumers into thinking that being gluten-free is a healthy choice.
But in reality, when a person who is not sensitive to gluten goes on a gluten-free diet, they are not only depriving themselves of nutritious foods made with wheat, but are also eliminating a good plant based protein from their diet and their health benefits. This is both unnecessary as well as expensive. It is quite unfortunate that merchants have capitalized on the gluten-free craze for profit without regarding how careless advertising may harm the consumer.
A celiac disease DNA test can tell you conclusively if you are sensitive to gluten. If you test negative for genetic variants in the HLA DQA and DQB genes, it means that your lifetime risk of developing celiac disease is almost zero (less than 0.04%). You can enjoy all the pasta and breads you like, and there is no need to go gluten free.
Some of the things you can find out from celiac disease DNA testing include:1. Whether you carry the HLA DQ2 and DQ8 haplotypes linked to gluten sensitivity
2. If you do not carry these alleles, your lifetime chance of developing celiac disease is extremely low, even if you eat gluten
What to look for in a Celiac Disease DNA test?With so many entertainment-based DNA tests on the market, it can be difficult identifying between genetics tests that are for entertainment purposes only versus the clinical grade DNA tests offered to physician and hospitals. There is a big difference.
Entertainment based celiac disease tests only look at a few DNA markers associated with the disease and cannot give you the big picture. It only looks at 2% of all of the possible genetic changes, which can cause Celiac disease. This means an entertainment-based test will provide you the results for a few selected DNA markers with the disclaimer that you need to take a clinical grade test to find out the complete picture. Here are some important considerations to ensure that you are purchasing a clinical grade test:
1. Is the entire HLA region sequenced using Sanger Sequencing?
2. Are all known HLA alleles tested for?
3.Is the test comprehensive, or are only a few SNPs examined?
DNA Celiac Disease Test
Overview:
The celiac disease DNA test that is offered by Genovate uses Sanger Sequencing to sequence the entire HLA region and then uses uTYPE® HLA Analysis software to conclusively determine your HLA genotype. It is a clinical grade test and will give you a comprehensive report on your risk of developing Celiac Disease.
The test is performed using a simple cheek swab and can be conducted on individuals at any age. What’s more, you do not need to eat gluten before doing the test. The DNA test can be performed at any time, regardless of your current diet.
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DNA Celiac Disease Testing Review
Features
Celiac Disease Test
HLA typing
Comprehensive test
Autosomal STR fragment analysis
Sanger Sequencing technology
Analyzes over 2000 base pairs of DNA
CLIA accredited
Proficiency tested
Comprehensive medical report